Obicetrapib reduces cholestrol level in high risk heart patients.
bicetrapib: Selective cholesteryl ester transfer protein inhibitor. It is intended to treat dyslipidemia . It works by inhibiting CETP , it is protein that is responsible for transfer of cholesterol between different lipoproteins.
Results
●It lowers LDL-C levels.
●It increase HDL levels.
●Obicetrapib can also decrease heart problems and stroke.
The new CTEP inhibitor obicetrapib can also decrease risk of ASCVD.
T IS ASCVD: ASCVD is atherosclerotic cardiovascular disease It’s a condition caused by the buildup of plaque inside arteries. It can cause cause decrease of blood flow to different organs. It can cause heart problems, stroke and other cardiovascular diseases.
Chest pain , shortness of breathe, fatigue and pain are leading symptoms of ASCVD.
ZETIMIBE: It treats high cholesterol by absorbing and reducing the amount of cholestrol from the food you eat. Cholesterol is a fatty substance in your blood that can block your blood vessels if levels become too high.
While comparing EZETIMIBE and Obicetrapib cholesterol level reduce by 40-50%.
European Atherosclerosis Society Congress 2025: The Broadway and tendem study shows obicetrapib can reduce LDL cholestrol. Tandem study evaluated a fixed-dose combination of obicetrapib and ezetimib in population. The broadway study is about how Obicetrapib can help in treating cardiovascular diseases and strokes.

Normal cholestrol levels:
●For men below 200 mg/dl ( 5.17 mmol/L)
●For women total cholesterol below 200 mg/dL, a non-HDL cholesterol below 130 mg/dL, and an LDL cholesterol below 100 mg/dL.
increase soluble fiber intake, balance diet, quit smoking and drinking , regular exercise and foods with added plant sterols or stanols they can help treating lower cholesterol levels and can also prevent heart diseases.
Conclusion:
Obicetrapib can reduce cardiovascular diseases and also can reduce LDL cholestrol levels . It offer’s a valuable treatment option for patient who are unable to reach target cholestrol levels with existing therapies. It effectiveness in decreasing heart diseases is a great advancement in scientific research which will also benefit doctors to treat patients more effectively. The end…..